How well do routine molecular diagnostics detect rifampicin heteroresistance in Mycobacterium tuberculosis?
K. C. S. Ng, P. Supply, F. Cobelens, C. Gaudin, J. Gonzalez-Martin, B. C. de Jong, L. Rigouts
This study evaluates the detection limits of rifampicin heteroresistance in four RDTs using mixed strains and Deeplex-MycTB, finding significant variation in sensitivity across tests.
bioRxiv · Aug 8, 2019Microbiology