Genetic Variant Burden Rises with BMI: Insights from Rare and Low-Frequency Variants in Obesity
Sumi Elsa John, Arshad Channanath, Md Zubbair Malik, ASHRAF AL MADHOUN, FAHD AL-MULLA, Alphonse Thanaraj Thangavel
The paper identifies rare and low-frequency genetic variants associated with obesity severity, finding that variant burden correlates with BMI across different obesity categories.
medRxiv · Oct 11, 2026 · PreprintGenetic & Genomic Medicine