Transcriptomic signature of Human Cardiac Fibroblast in Hypertrophic Obstructive Cardiomyopathy
Ayman Maher Ibrahim, Sarah Halawa, Lydia Sidarous, Aya A. Galal, Sara Elshorbagy, Hasnaa A. Elfawy, Manar Osman, Faisal Mohamed, Mohamed Roshdy, Mohamed Hosny, Arwa Kohela, Mona Allouba, Ahmed Moustafa, Yasmine Aguib, Magdi Habib Yacoub
This study identifies a distinct transcriptomic signature in HOCM cardiac fibroblasts, highlighting inflammatory signaling, ECM remodeling, and altered cell-matrix communication.
bioRxiv · Jul 17, 2026 · PreprintCell Biology