Reliable prediction of protein-protein binding affinity changes upon mutations with Pythia-PPI
Fangting Tao, Jinyuan Sun, Pengyue Gao, George Fu Gao, Bian Wu
Pythia-PPI improves prediction of protein-protein binding affinity changes by using multi-task learning and self-distillation, achieving higher accuracy than existing methods.
National Science Review · May 5, 2025Peer-reviewedBioinformatics