Visualize, Explore, and Select: A protein Language Model-based Approach Enabling Navigation of Protein Sequence Space for Enzyme Discovery and Mining
Felix Moorhoff, David Medina-Ortiz, Alicja Kotnis, Ahmed Hassanin, Mehdi D. Davari
The paper introduces SelectZyme, a platform using protein language models and dimensionality reduction to visualize and explore protein sequence space for enzyme discovery, enabling candidate selection without relying on sequence identity or annotations.
bioRxiv · Mar 25, 2026 · PreprintBioinformatics