BioinformaticsNucleic Acids ResearchPeer-reviewed
LTMG (Left truncated mixture Gaussian) based modeling of transcriptional regulatory heterogeneities in single cell RNA-seq data - a perspective from the kinetics of mRNA metabolism
Changlin Wan, Wennan Chang, Yu Zhang…·Chi Zhang
The paper introduces LTMG, a model for capturing transcriptional regulatory heterogeneities in scRNA-seq data, showing improved fitting and validation on multiple datasets.
45 citations