One Health in Eastern Africa: No barriers for ESBL producing E. coli transmission or independent antimicrobial resistance gene flow across ecological compartments
Patrick Musicha, Mathew A. Beale, Derek Cocker, Fiona A Oruru, Allan M. Zuza, Chifundo Salifu, George Katende, Sylvia Nanono, Fred Isaasi, Kondwani Chidziwisano, Lawrence Mugisha, Henry Kajumbula, David Musoke, Tracy Morse, Shevin T. Jacob, , Nicholas Robert Thomson
The paper uses whole genome sequencing to show high diversity and transmission of ESBL-Ec across human, animal, and environmental compartments in low-income settings, supporting the One Health approach for AMR control.
bioRxiv · Sep 18, 2024 · PreprintGenomics