Chronic cocaine exposure negatively impacts Long-COVID-like outcomes produced by the SARS-CoV-2 spike protein in the rat
Sarah E Davis, Danielle R Stern, Saadet Inan, Emily Vu, Daniel Lopez, Flourish Anwuri, Marco Ghilotti, Joseph J. Meissler, Ellen M. Unterwald
This study shows that chronic cocaine exposure worsens Long-COVID-like outcomes in rats after SARS-CoV-2 spike protein exposure, including reduced weight gain, increased pain sensitivity, and altered behavior.
bioRxiv · Jun 2, 2026 · PreprintNeuroscience