N-Gene and T-Gene Deregulation Networks: A data-driven causal framework for the analysis of gene interventions in cancer
Frank Castel, Roberto Herrero, Jean Pierre Gómez, Gabriel Gil, Augusto González
The paper introduces Gene Deregulation Networks (GDNs) to analyze gene interventions in cancer by constructing networks from gene expression data without prior functional annotations.
Frontiers in Systems Biology · Jul 2, 2026Peer-reviewedSystems Biology