Combination Drug Therapy Reduces Iron Accumulation and Microglia-Mediated Pathologies in Neonatal Intraventricular Hemorrhage: A Biochemical and Transcriptomic Analysis
Vanessa Castro Diaz, Michelle Sunshine, Furong Hu, Sohan Shah, Weihua Huang, Carl I. Thompson, Michael S. Wolin, Selvakumar Subbian, Edmund F. LaGamma, Govindaiah Vinukonda
This study shows that sulforaphane and deferoxamine combination therapy reduces inflammation and iron toxicity in neonatal intraventricular hemorrhage by modulating microglia and gene expression.
Frontiers in Cellular Neuroscience · May 25, 2026Peer-reviewedNeuroscience