Epigenetic Profiling for the Molecular Classification of Metastatic Brain Tumors
J. I. J. Orozco, T. A. Knijnenburg, A. O. Manughian-Peter, M. P. Salomon, G. Barkhoudarian, J. R. Jalas, J. S. Wilmott, P. Hothi, X. Wang, Y. Takasumi, M. E. Buckland, J. F. Thompson, G. V. Long, C. S. Cobbs, I. Shmulevich, , D. M. Marzese
This study develops a DNA methylation-based classifier, BrainMETH, to categorize brain metastases by tissue origin and therapeutic subtypes using epigenetic profiling.
bioRxiv · Feb 22, 2018Cancer Biology