Detection of early stage pancreatic cancer using 5-hydroxymethylcytosine signatures in circulating cell free DNA
F. Collin, Y. Ning, T. Phillips, E. McCarthy, A. Scott, C. Ellison, C.-J. Ku, G. D. Guler, K. Chau, A. Ashworth, S. R. Quake, S. Levy
This study identifies 5-hydroxymethylcytosine (5hmC) signatures in circulating cell-free DNA to detect early-stage pancreatic cancer with high accuracy.
bioRxiv · Sep 26, 2018Cancer Biology