Automated Protein Affinity Optimization using a 1D-CNN Deep Learning Model
J. L. McWhirter, A. Mukhopadhyay, P. Farber, G. Lakatos, S. Dixit
This paper introduces ZymeSwapNet, a 1D-CNN model for protein sequence prediction that optimizes design objectives like stability and binding specificity in antibody domains.
bioRxiv · Apr 12, 2023 · PreprintBioengineering