A Polygenic Score for Reduced Kidney Function and Adverse Outcomes in a Chronic Kidney Disease Cohort
Inga Steinbrenner, Zhi Yu, Jin Jin, Ulla T. Schultheiß, Fruzsina Kotsis, Morgan Erika Grams, Josef Coresh, Matthias Wuttke, Gckd study investigators, Florian Kronenberg, Kai‐Uwe Eckardt, Nilanjan Chatterjee, Peggy Sekula, Anna Köttgen
The paper assesses if a polygenic score for reduced kidney function predicts adverse outcomes in chronic kidney disease patients, finding significant associations but no improvement in prediction over existing risk equations.
Kidney International · Dec 5, 2022Peer-reviewedGenetic & Genomic Medicine