Evidence of fitness costs associated with Ace-1R-mediated resistance to pirimiphos-methyl in Anopheles gambiae sensu lato following the withdrawal of indoor residual spraying in Burkina Faso
Karama O. Delphine, Aristide S. Hien, Dieudonné Diloma Soma, Kelly Lionelle Ngaffo, Samina Maiga, Didier P. Alexandre Kaboré, Rabila Bamogo, Georges Benson Meda, Moussa Namountougou, Roch K. Dabiré
This study shows that stopping indoor residual spraying in Burkina Faso led to reduced Ace-1 resistance allele frequencies and restored susceptibility to pirimiphos-methyl, suggesting biological costs of resistance.
bioRxiv · Aug 10, 2026 · PreprintZoology