Effects of kinship correction on inflation of genetic interaction statistics in commonly used mouse populations
Anna L. Tyler, Bahá El Kassaby, Georgi Kolishovski, Jake Emerson, Ann Wells, J. Matthew Mahoney, Gregory W. Carter
This study examines how kinship correction affects genetic interaction test statistics in mouse populations, finding no inflation in interaction tests but recommending reduced kinship matrices for better correction.
G3 Genes Genomes Genetics · Apr 23, 2021Peer-reviewedGenetics