LIET Model: Capturing the kinetics of RNA polymerase from loading to termination
Jacob T. Stanley, Georgia E F Barone, Hope A. Townsend, Rutendo F. Sigauke, Mary Ann Allen, Robin D. Dowell
The paper introduces the LIET model to analyze RNA polymerase kinetics across transcription stages and applies it to human cell-types and perturbation experiments to detect changes in transcription dynamics.
Nucleic Acids Research · Apr 9, 2025Peer-reviewedBioinformatics