Author

Gerrit Vriend

Radboud University Nijmegen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 2 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:variant effect prediction· 2 Assay:whole-exome sequencing· 2 Research Focus:benchmarking· 1 Research Focus:database / resource· 1 Approach:deep learning· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Christian GilisseniD· 2 shared Joris Andre VeltmaniD· 2 shared Laurens WieliD· 2 shared Andrea SchafferhansiD· 1 shared Avner SchlessingeriD· 1 shared Burkhard RostiD· 1 shared Chris SanderiD· 1 shared Christian DallagoiD· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Christian GilissenORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

De novo mutation hotspots in homologous protein domains identify function-altering mutations in neurodevelopmental disorders

Laurens Wiel, Juliet E. Hampstead, Hanka Venselaar, Lisenka E.L.M. Vissers, Han G. Brunner, Rolph Pfundt, Gerrit Vriend, Joris Andre Veltman, Christian Gilissen

The paper identifies function-altering de novo mutations in neurodevelopmental disorders by analyzing mutational hotspots across homologous protein domains.

The American Journal of Human Genetics · Dec 22, 2022Peer-reviewedGenetic & Genomic Medicine

PredictProtein - Predicting Protein Structure and Function for 29 Years

Michael Bernhofer, Christian Dallago, Tim Karl, Venkata Satagopam, Michael Heinzinger, Maria Littmann, Tobias Olenyi, Jiajun Qiu, Konstantin Schütze, Guy Yachdav, Haim Ashkenazy, Nir Ben‐Tal, Yana Bromberg, Tatyana Goldberg, László Kaján, , Burkhard Rost

PredictProtein provides protein sequence analysis tools, offering structure and function predictions with updates including deep learning and DNA/RNA/protein binding predictions.

bioRxiv · Feb 23, 2021 · PreprintBioinformatics

MetaDome: Pathogenicity analysis of genetic variants through aggregation of homologous human protein domains

Laurens Wiel, Coos A. B. Baakman, Daan Gilissen, Joris Andre Veltman, Gerrit Vriend, Christian Gilissen

MetaDome provides a web service to analyze genetic variants by aggregating homologous human protein domains, improving interpretation of variants of unknown significance.

Human Mutation · May 22, 2019Peer-reviewedBioinformatics