Non-standard proteins in the lens of AlphaFold3 - a case study of amyloids
Alicja W. Wojciechowska, Jakub Wiktor Wojciechowski, Gert Vriend, Małgorzata Kotulska
This paper evaluates AlphaFold3's ability to predict amyloid structures using three datasets, finding it performs better on known fibrillar structures but struggles with non-fibrillar and short fragments.
Scientific Reports · Sep 3, 2026Peer-reviewedBioinformatics