A natural encoding of genetic variation in a Burrows-Wheeler Transform to enable mapping and genome inference
Sorina Maciuca, Carlos del Ojo Elias, Gil McVean, Zamin Iqbal
This paper encodes genetic variation into a Burrows-Wheeler Transform to improve genome inference and mapping by incorporating known variation into a generalized reference genome.
bioRxiv · Jul 25, 2016 · PreprintBioinformatics