In-silico modelling of the mitogen-activated kinase (MAPK) pathway in colorectal cancer: mutations and targeted therapy
Sara Sommariva, Silvia Berra, Giorgia Biddau, Giacomo Caviglia, Federico Benvenuto, Michele Piana
The paper uses chemical reaction networks to model the MAPK pathway in colorectal cancer, analyzing mutation effects and simulating multi-target therapy.
bioRxiv · Apr 18, 2023 · PreprintSystems Biology