HDAC6 promotes PMA-induced megakaryocyte differentiation of K562 cells by regulating ROS levels via NOX4 and repressing Glycophorin A
Githavani Kummari, Ravi Kumar Gutti, Arunasree Marasanapalli Kalle
This study shows HDAC6 promotes PMA-induced megakaryocyte differentiation in K562 cells by increasing ROS via NOX4 and repressing the erythroid marker GYPA.
bioRxiv · Mar 14, 2019 · PreprintDevelopmental Biology