An evolutionary compass for detecting signals of polygenic selection and mutational bias
L. H. Uricchio, H. C. Kitano, A. Gusev, N. A. Zaitlen
This paper develops a statistical method to detect mutational bias and selection signals using GWAS data, finding evidence for non-neutral processes in traits like BMI and schizophrenia.
Evolution Letters · Feb 1, 2019Peer-reviewedEvolutionary Biology