Author

H. Kohestani

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Biology Disciplines

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Research Focus:chromatin & epigenetic regulation· 2 Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:clustering· 1 Assay:DNA methylation· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

J. Weresczczynski· 1 shared J. Wereszczynski· 1 shared

Activity by Year

2020-2022 · peak 1/yr

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2 top collaborators · 0 mutual co-author links

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1 shared paperBiophysics

J. Weresczczynski

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2 papers

Recent·Most cited

The Effects of RNA.DNA-DNA Triple Helices on Nucleosome Structures and Dynamics

H. Kohestani, J. Wereszczynski

This study uses molecular dynamics simulations to investigate how RNA.DNA-DNA triple helices affect nucleosome structure and dynamics, revealing RNA sequence effects and interactions with histone tails.

bioRxiv · Jul 2, 2022Biophysics

Effects of H2A.B incorporation on nucleosome structures and dynamics

H. Kohestani, J. Weresczczynski

This study uses molecular dynamics simulations to show that H2A.B incorporation reduces nucleosome compactness by weakening protein-DNA and protein-protein interactions, increasing DNA accessibility and transcription.

bioRxiv · Jun 25, 2020Biophysics