Author

H. Kruse

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:mechanistic / dynamical model· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:cryo-EM· 1 Approach:deep learning· 1 Assay:DNA methylation· 1 Research Focus:protein folding & dynamics· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

J. Sponer· 2 shared K. Mrazikova· 2 shared M. Krepl· 2 shared J. Voegele· 1 shared J. Woehnert· 1 shared M. Biczysko· 1 shared M. Otyepka· 1 shared M. P. Waller· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersBiophysics

J. Sponer

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Optimal clustering for quantum refinement of biomolecular structures: Q|R#4

Y. Wang, H. Kruse, N. W. Moriarty, M. P. Waller, P. V. Afonine, M. Biczysko

This paper validates and optimizes a divide-and-conquer procedure for quantum refinement of biomolecular structures, introducing an error score to guide computational efficiency.

bioRxiv · Nov 24, 2022Biochemistry

Phosphorothioate Substitutions in RNA Structure Studied by Molecular Dynamics Simulations, QM/MM Calculations and NMR Experiments

Z. Zhang, J. Voegele, K. Mrazikova, H. Kruse, X. Cang, J. Woehnert, M. Krepl, J. Sponer

This study investigates how phosphorothioate substitutions affect RNA structure and dynamics using MD simulations, QM/MM calculations, and NMR experiments on a riboswitch model.

bioRxiv · Oct 28, 2020Biophysics

UNCG RNA tetraloop as a formidable force-field challenge for MD simulations

K. Mrazikova, V. Mlynsky, P. Kuhrova, P. Pokorna, H. Kruse, M. Krepl, M. Otyepka, P. Banas, J. Sponer

This study analyzes MD simulations of the UNCG RNA tetraloop, identifying force field deficiencies that contribute to its instability in simulations.

bioRxiv · Jul 27, 2020 · PreprintBiophysics