Systems biology analysis of vasodynamics in mouse cerebral arterioles during resting state and functional hyperemia
Hadi Esfandi, Mahshad Javidan, Eric R. McGregor, Rozalyn M. Anderson, Ramin Pashaie
This study develops a biophysical model of arteriolar vasodynamics in mice, revealing how neurogenic, astrocytic, and myogenic responses interact to regulate cerebral hemodynamics during rest and activation.
PLoS Computational Biology · Apr 27, 2026Peer-reviewedNeuroscience