Author

Hai-Feng Chen

Shanghai Jiao Tong University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 2

Signature Assays, Organisms & Methods

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Assay:protein structure· 2 Research Focus:benchmarking· 1 Approach:deep learning· 1 Assay:DNA methylation· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

Junjie ZhuiD· 1 shared Kaipeng Zheng· 1 shared Kresten Lindorff‐LarseniD· 1 shared Liu Cheng· 1 shared Weiran HuangiD· 1 shared Zhangsheng YuiD· 1 shared Zhengxin LiiD· 1 shared Zhuoqi ZhengiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 16 mutual co-author links

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1 shared paperBioinformatics

Junjie ZhuORCID

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2 papers

Recent·Most cited

Probing Physical Intuition in Large Language Models through Partner-Dependent Mutation Prediction

Liu Cheng, Kaipeng Zheng, Weiran Huang, Hai-Feng Chen, Zhangsheng Yu

This study evaluates LLMs' ability to predict mutation effects based on structural data without using dedicated predictors, finding comparable accuracy to existing methods.

bioRxiv · Oct 12, 2026 · PreprintBioinformatics

StruCloze: A Unified Framework for Backmapping and Inpainting of Biomolecules

Junjie Zhu, Zirui Fan, Zhengxin Li, Zhuoqi Zheng, Kresten Lindorff‐Larsen, Hai-Feng Chen

StruCloze reconstructs atomistic structures from coarse-grained models and inpaints missing regions in biomolecules, achieving state-of-the-art accuracy and transferability.

bioRxiv · Jun 26, 2025 · PreprintBioinformatics