Fine-Tuning Protein Language Models Enhances the Identification and Interpretation of the Transcription Factors
Mir Tanveerul Hassan, Saima Gaffar, Hamza Zahid, Bilal Ahmad, Sang Jun Lee
This paper introduces a two-layer framework using protein language models to identify transcription factors and predict TFs with methylated DNA binding preferences, achieving better performance than existing methods.
Artificial Intelligence in the Life Sciences · Apr 24, 2026Peer-reviewedBioinformatics