Lipid-Driven Biophysical Selection of β-Furanoside-5'-Phosphate as the Sole Scaffold of Extant RNA
Ze-Run Zhao, Qian-Qian Chen, Hao-Xing Xu, Bing-Yue Zhao, Cheng-Cheng Gu, Xiao Wang
This study identifies β-furanoside-5'-phosphate as the preferred RNA scaffold through biophysical selection, showing its enhanced lipid permeability and enrichment in protocells.
bioRxiv · May 29, 2026 · PreprintBiophysics