Author

Haoyu Lu

Soochow University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 2

Signature Assays, Organisms & Methods

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Assay:protein sequence· 2 Research Focus:variant effect prediction· 2 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:machine learning (classical)· 1 Research Focus:protein design· 1 Assay:protein structure· 1 Approach:statistical model· 1

Frequent Co-Authors

Shuqin WangiD· 2 shared Yuting CheniD· 2 shared Zefeng ZhuiD· 2 shared Minghui LiiD· 1 shared Minghui LiiD· 1 shared Ning ZhangiD· 1 shared Ning ZhangiD· 1 shared Qing YangiD· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

8 top collaborators · 22 mutual co-author links

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2 shared papersBioinformatics

Shuqin WangORCID

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2 papers

Recent·Most cited

PremPS: Predicting the Effects of Single Mutations on Protein Stability

Yuting Chen, Haoyu Lu, Ning Zhang, Zefeng Zhu, Shuqin Wang, Minghui Li

PremPS predicts the effects of single mutations on protein stability and pathogenicity using a machine learning model trained on five thousand mutations.

PLoS Computational Biology · Dec 30, 2020Peer-reviewedBioinformatics

PremPRI: Predicting the Effects of Single Mutations on Protein-RNA Interactions

Ning Zhang, Haoyu Lu, Yuting Chen, Zefeng Zhu, Qing Yang, Shuqin Wang, Minghui Li

PremPRI predicts the effects of single mutations on protein-RNA interactions using a regression model trained on experimental data, achieving high correlation with experimental binding affinity changes.

International Journal of Molecular Sciences · Aug 3, 2020Peer-reviewedBioinformatics