Quantifying polygenic effects in genome-wide association studies using generalized estimating equations
Julian Hecker, Dmitry Prokopenko, Christoph Lange, Heide Löhlein Fier
This paper extends LD Score regression using generalized estimating equations to better quantify polygenic effects in GWAS by incorporating external reference panel information.
bioRxiv · Nov 25, 2015 · PreprintBioinformatics