The Aspergillus nidulans velvet domain containing transcription factor VeA is shuttled from cytoplasm into nucleus during vegetative growth and stays there for sexual development, but has to return into cytoplasm for asexual development
Anja Strohdiek, Anna M. Köhler, Rebekka Harting, Helena Stupperich, Jennifer Gerke, Emmanouil Bastakis, Piotr Neumann, Yasar Luqman Ahmed, Ralf Ficner, Gerhard H. Braus
The paper shows that VeA, a fungal transcription factor, shuttles between the cytoplasm and nucleus during different developmental stages, with nuclear localization required for sexual development and cytoplasmic presence needed for asexual development.
PLoS Genetics · Jun 16, 2025Peer-reviewedMolecular Biology