Chances and challenges of machine learning based disease classification in genetic association studies illustrated on age-related macular degeneration
Felix Günther, Caroline Brandl, Thomas W. Winkler, Veronika Wanner, Klaus J. Stark, Helmut Kuechenhoff, Iris M. Heid
The paper applies machine learning to classify age-related macular degeneration in GWAS, showing how misclassification can be addressed to identify true genetic associations.
Genetic Epidemiology · Aug 2, 2020Peer-reviewedGenetics