Towards Understanding the Drivers of Antibody-Antigen Binding
Omeir Khan, Marcus Kankkunen, Michel Shaker, Henry Chow, Nikolas Moustakas, Siri Allegra-Berger, Maria Lazou, Sándor Vajda, Diane Joseph‐McCarthy
The paper uses FTMap to analyze 50 antibody-antigen complexes, finding that paratopes are hot spot-rich and that Trp/Tyr residues drive hot spot formation.
Biophysical Journal · Feb 12, 2026Peer-reviewedBioinformatics