Coupling mathematical modeling with a novel human intestinal stem cell system to understand feedback regulation during planar cell polarity
Keith A. Breau, Emma G. Dunahey, Henry V. Fosnocht, Scott T. Magness, Timothy C. Elston
The paper develops a mathematical model of the PCP complex and validates its predictions using a human intestinal stem cell system to study feedback regulation during planar cell polarity.
bioRxiv · Nov 5, 2025 · PreprintSystems Biology