Longitudinal differential abundance analysis of microbial marker-gene surveys using smoothing splines
Joseph Nathaniel Paulson, Hisham Talukder, Héctor Corrada Bravo
The paper introduces a method using smoothing splines to analyze longitudinal microbial marker-gene data, identifying time periods of differential abundance across sample groups.
bioRxiv · Jan 10, 2017 · PreprintGenomics