From neuropeptide and receptor annotation to ligand-receptor pairing: a sequence- and structure-based framework for mapping the neuropeptide-receptor interactome in Gryllus bimaculatus
Febrina Margaretha, Mika Sakamoto, Hitomi Seike, Shinji Nagata, Yasukazu Nakamura, Takako Mochizuki
The paper annotates neuropeptides and GPCRs in Gryllus bimaculatus and predicts ligand-receptor pairs using AlphaFold3 and Boltz-2, providing a resource for studying insect endocrinology.
bioRxiv · Sep 3, 2026 · PreprintBioinformatics