Evolution of hierarchical switching pattern in antigenic variation of Plasmodium falciparum under variable host immunity
Gayathri Priya Iragavarapu, HJ Varsha, Shruthi Sridhar Vembar, Bhaswar Ghosh
The paper shows that variable switching rates of var genes in Plasmodium falciparum provide an evolutionary advantage by optimizing parasite survival under host immune pressure.
bioRxiv · Aug 30, 2023 · PreprintSystems Biology