Decoding the transcriptome of denervated muscle at single-nucleus resolution
Hongchun Lin, Xinxin Ma, Yuxiang Sun, Hui Peng, Yanlin Wang, Sandhya S. Thomas, Zhaoyong Hu
This study uses snRNA-seq to analyze denervated muscle, identifying transcriptional changes in specific myonuclei subtypes and revealing gene regulatory networks and metabolic shifts associated with muscle atrophy.
Journal of Cachexia Sarcopenia and Muscle · Jun 20, 2022Peer-reviewedMolecular Biology