Caloric Restriction Remodels Energy Metabolic Pathways of Gut Microbiota and Promotes Host Autophagy
Yuping Yang, Shaoqiu Chen, Yumin Liu, Yuanlong Hou, Xie Xie, Xia Zhang, Aihua Zhao, Xiaojiao Zheng, Jiajian Liu, Tianlu Chen, Tianma Yuan, Hongjing Yu, Chongchong Wang, Yifan Sun, Jingcheng Wang, , Wei Ping Jia
This study shows that caloric restriction increases malate and related metabolites, remodels gut microbiota energy metabolism, and promotes host autophagy through a functional metabolic network.
bioRxiv · Aug 16, 2020 · PreprintSystems Biology