Ether-lipid deficiency remodels the testicular interstitium beyond spermatogenic arrest in Gnpat-knockout mice
Md. Shamim Hossain, Akihisa Fujiyama, Honsho Masanori, Shiro Mawatari, Takehiko Fujino
This study shows that Gnpat-knockout mice exhibit testicular interstitial remodeling and germ-cell loss due to ether-lipid deficiency, with no DNA-damage checkpoint activation.
bioRxiv · Oct 22, 2026 · PreprintPhysiology