A Global Thermodynamic-Kinetic Model Capturing the Hallmarks of Liquid-Liquid Phase Separation and Amyloid Aggregation
Kamal Bhandari, Yunxiang Sun, Huayuan Tang, Pu Chun Ke, Feng Ding
This paper develops a thermodynamic-kinetic model that integrates liquid-liquid phase separation with amyloid aggregation to resolve conflicting effects of LLPS on fibrillization.
Cell Reports Physical Science · Dec 23, 2025Peer-reviewedBiophysics