Genome-wide CNV study and functional evaluation identified CTDSPL as tumour suppressor gene for cervical cancer
Dan Chen, Shuai Wang, Zhenli Li, Tao Cui, Yao Chen, Junjiao Song, Patrik KE Magnusson, Huibo Wang, Dandan Zhang, Ulf Gyllensten
The paper identifies a deletion in CTDSPL as a strong genetic risk variant for cervical cancer, showing it suppresses tumor growth in vitro and in vivo.
bioRxiv · Jun 22, 2018 · PreprintCancer Biology