Proton-control of transitions in an amino-acid transporter
Z. Wu, I. Alibay, S. Newstead, P. C. Biggin
The paper uses molecular dynamics simulations to study proton-coupled amino acid transport in GkApcT, showing that deprotonation of E115 facilitates the transition from inward-occluded to inward-open states.
bioRxiv · Apr 11, 2019Biophysics