I. Baldea

Antioxidant Activity via Free Radical Scavenging of Pitavastatin and Its Hydroxylated Metabolites. A Quantum Chemical Attempt Aiming to Assist Drug Development

This paper uses quantum chemical calculations to predict the antioxidant activity of pitavastatin and its hydroxylated metabolites, suggesting they have superior antioxidant properties compared to the parent compound.

Why Ortho- and Para-Hydroxy Metabolites Can Scavenge Free Radicals That the Parent Atorvastatin Cannot? Important Pharmacologic Insight from Quantum Chemistry

The paper uses quantum chemistry to explain why hydroxy metabolites of atorvastatin are more effective than the parent drug in scavenging free radicals.

Critical analysis of radical scavenging properties of atorvastatin in methanol recently estimated via density functional theory

The paper identifies and corrects errors in previously reported antioxidant properties of atorvastatin in methanol using density functional theory.