Immunoregulatory subtype of dermal lymphatic endothelial cells at capillary terminals drives lymphatic malformations
M. Petkova, M. Kraft, S. Stritt, I. Martinez-Corral, H. Ortsater, Y. Sun, M. Vanlandewijck, B. Jakic, E. Baselga, S. D. Castillo, M. Graupera, C. Betsholtz, T. Makinen
The paper identifies an immunoregulatory subtype of lymphatic endothelial cells that drives lymphatic malformations through pro-inflammatory signaling and immune cell interactions.
bioRxiv · May 22, 2022Cell Biology