Higher temperatures worsen the effects of mutations on protein stability
D. - G. Kontopoulos, I. Patmanidis, T. G. Barraclough, S. Pawar
This study shows that higher temperatures amplify the destabilizing effects of mutations on protein stability in prokaryotes, leading to decreased mutation rates with increasing temperature.
bioRxiv · Oct 13, 2020 · PreprintEvolutionary Biology