Author

I. Sela

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 4 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 5 Organism:bacteria (other)· 4 Research Focus:chromatin & epigenetic regulation· 4 Assay:whole-genome sequencing· 4 Organism:virus· 2 Approach:Bayesian inference· 1 Assay:DNA methylation· 1 Research Focus:phylogenetics / evolution· 1

Frequent Co-Authors

E. V. Koonin· 4 shared Y. I. Wolf· 4 shared E. Koonin· 1 shared F. Belinky· 1 shared I. B. Rogozin· 1 shared J. Iranzo· 1 shared

Activity by Year

2017-2021 · peak 2/yr

Co-Author Collaboration Network

6 top collaborators · 7 mutual co-author links

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4 shared papersEvolutionary Biology

E. V. Koonin

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5 papers

Recent·Most cited

Horizontal gene transfer barrier shapes the evolution of prokaryotic pangenomes

I. Sela, Y. I. Wolf, E. V. Koonin

The paper examines the evolutionary factors shaping the U-shaped gene commonality distribution in prokaryotic pangenomes and identifies the horizontal gene transfer barrier as a key factor.

BMC Biology · Feb 10, 2021Peer-reviewedEvolutionary Biology

Homologous recombination substantially delays sequence but not gene content divergence of prokaryotic populations

J. Iranzo, Y. I. Wolf, E. V. Koonin, I. Sela

The paper shows homologous recombination delays sequence divergence but not gene content divergence in prokaryotic populations, explaining rapid gene turnover before significant sequence divergence.

bioRxiv · Jan 11, 2019Evolutionary Biology

Crossing fitness valleys via double substitutions within codons

F. Belinky, I. Sela, I. B. Rogozin, E. V. Koonin

The paper analyzes double substitutions within codons to determine how selection pressures differ across substitution classes and how they affect fitness valley crossing.

bioRxiv · Jan 4, 2019Evolutionary Biology

Genome plasticity, a key factor of evolution in prokaryotes

I. Sela, Y. I. Wolf, E. V. Koonin

The paper identifies genome plasticity and selection landscape as key factors driving gene content evolution in prokaryotes through mathematical modeling and analysis of microbial genomes.

bioRxiv · Jun 27, 2018Microbiology

Estimation Of Universal And Taxon-Specific Parameters Of Prokaryotic Genome Evolution

I. Sela, Y. I. Wolf, E. Koonin

The paper refines a mathematical model of microbial genome evolution by incorporating group-specific factors, finding a mean selection coefficient of ~10^-10 and a deletion bias greater than unity.

bioRxiv · May 12, 2017Evolutionary Biology