NeuroscienceGeroSciencePeer-reviewed
Lipid-laden endothelial cells exhibit a transcriptomic signature linked to blood-brain barrier dysfunction, metabolic reprogramming and increased inflammation in the aging brain
Sarah Otu-Boakye, Duraipandy Natarajan, Bhuvana Plakkot…·Priya Balasubramanian
This study identifies a transcriptomic signature in aged brain endothelial cells linked to lipid accumulation, BBB dysfunction, metabolic changes, and inflammation.