Author

Irene J. Castillo

National Institutes of Health

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Organism:human· 1 Assay:imaging· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Benjamin D. SolomoniD· 1 shared Carlos R. FerreiraiD· 1 shared Dat DuongiD· 1 shared Francis RossignoliD· 1 shared Kendall A. FlahartyiD· 1 shared Ping HuiD· 1 shared Rebekah L. WaikeliD· 1 shared Suzanna E. Ledgister HanchardiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperGenetic & Genomic Medicine

Benjamin D. SolomonORCID

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Author profile →

1 paper

Recent·Most cited

Deep Learning Study of Alkaptonuria Spinal Disease Assesses Global and Regional Severity and Detects Occult Treatment Status

Kendall A. Flaharty, Vibha Chandrasekar, Irene J. Castillo, Dat Duong, Carlos R. Ferreira, Suzanna E. Ledgister Hanchard, Ping Hu, Rebekah L. Waikel, Francis Rossignol, Wendy J. Introne, Benjamin D. Solomon

This study uses deep learning to assess spinal severity in alkaptonuria, predict treatment status, and compare performance with clinicians.

Journal of Inherited Metabolic Disease · May 1, 2025Peer-reviewedGenetic & Genomic Medicine